Top Left: A very handsome young boy and a cute terrier dog are used to advertise "Dr. Thatcher's Mixture" for "Diarrhoea [sic] Due to Dietary Indiscretions", by the Thatcher Medicine Co. in Chattanooga, Tenn. There is no mention of the artist, unfortunately.
Bottom: A charming girl with a red ball and her chubby brother, holding a cocker spaniel, are advertising Hobby's Grocery and Market in Cary, N.C. Note the Phone number: 21. That had to be in the 1940's or before. This fan is not signed by the artist either.